ABSTRACT
The increasing exposure of the medical professions in general and obstetricians in particular to claims for damages or negligence seeks to perform this descriptive cross-sectional study that was carried out to assess physician's knowledge, attitude and practice about bioethics related to the field of gynecology and obstetrics. Data were collected by using a pre-designed questionnaire. The target group was all physicians working in this field in both Suez Canal University Hospital and Ismailia General Hospital, their number were 66 physicians. The study demonstrated that physician's knowledge was not significantly affected by their place of work [P > 0.05], but was significantly affected by their scientific degree and by the duration of their clinical practice [P<0.05], physician's attitude wasn't significantly affected by any of those factors [P > 0.05] and physician's practice was significantly affected by their place of work, their scientific degree and the duration of their clinical practice [P<0.05]
Subject(s)
Humans , Female , Health Knowledge, Attitudes, Practice , Health Personnel , Obstetrics and Gynecology Department, Hospital/ethics , Physicians , Surveys and Questionnaires , Hospitals, University/ethics , Hospitals, General/ethicsABSTRACT
The Two methods [TLC and HPLC] were applied to the head hair of epileptic patients who are orally treated with 100, 150, 200 and 300 mg of phenytoin daily. The detection of phenytoin in human hair revealed that, by TLC phenytoin was present in all hair samples. Zwikker's reagent and the dithiazone reagent were the best spraying reagents when the eluent was methanol to chloroform 1:9 by HLPC, phenytoin was present in hair samples at concentrations ranged from 4.3-9.5 ng/mg after administration of 100-300 mg/day of phenytoin respectively with a retention time 6.16 min when the mobile phase was Acetonitrile 70% to methanol 30%. The results show a linear correlation between the drug concentration in human hair and the daily dosage of phenytoin